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- CBD News
CBD Treatment of Infantile Batten Fails to Reduce Seizures in Mice: Study | Cannabidiol was found to reduce brain inflammation in a mouse model
Six months of cannabidiol (CBD) treatment reduced brain inflammation in a mouse model of infantile Batten disease, but did not affect seizure frequency or nerve cell survival, a new study reports. Given the severe symptoms that typically characterize this subtype of Batten disease, the researchers note that the dosage used in this study may simply not have been sufficient. “It…
Read More » Effects of chronic cannabidiol in a mouse model of naturally occurring neuroinflammation, neurodegeneration, and spontaneous seizures
Animals One cohort of mice consisted of 14 mice [5 Cln1−/− mice treated with CBD, 5 Cln1−/− mice treated with vehicle, and 4 untreated wild-type (WT) mice] to be used for immunofluorescence and cytokine analysis. A second cohort of untreated Cln1−/− mice was used to evaluate the development and trajectory of seizures and determine an optimum seizure observation window; this…
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